All Phenotypes Metrnl<tm1d(KOMP)Wtsi> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Metrnl^{tm1d(KOMP)Wtsi}
targeted mutation 1d, Wellcome Trust Sanger Institute
MGI:6367587

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Metrnl^{tm1d(KOMP)Wtsi}/Metrnl^{tm1d(KOMP)Wtsi}	involves: C57BL/6J * C57BL/6N	MGI:6367637

Allelic Composition	Metrnl^{tm1d(KOMP)Wtsi}/Metrnl^{tm1d(KOMP)Wtsi}
Genetic Background	involves: C57BL/6J * C57BL/6N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Metrnl^{tm1d(KOMP)Wtsi} mutation (1 available); any Metrnl mutation (31 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

increased susceptibility to induced morbidity/mortality ( J:268270 )

• in response to LPS-treatment

immune system

decreased IgG level ( J:268270 )

• in the serum

increased IgM level ( J:268270 )

• in the serum

increased susceptibility to endotoxin shock ( J:268270 )

• with increased mortality

liver inflammation ( J:268270 )