All Phenotypes Tmprss11b<em2Bug> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tmprss11b^em2Bug
endonuclease-mediated mutation 2, Thomas H Bugge
MGI:6364132

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Tmprss11a^em3Bug/Tmprss11a^em3Bug Tmprss11b^em2Bug/Tmprss11b^em2Bug Tmprss11c^em3Bug/Tmprss11c^em3Bug Tmprss11d^em3Bug/Tmprss11d^em3Bug Tmprss11e^em2Bug/Tmprss11e^em2Bug Tmprss11g^em2Bug/Tmprss11g^em2Bug	FVB/NJ-Tmprss11c^em3Bug Tmprss11d^em3Bug Tmprss11a^em3Bug Tmprss11g^em2Bug Tmprss11b^em2Bug Tmprss11e^em2Bug	MGI:6364583
cx2	Tmprss11a^em3Bug/Tmprss11a^em3Bug Tmprss11b^em2Bug/Tmprss11b^em2Bug Tmprss11c^em3Bug/Tmprss11c^em3Bug Tmprss11d^em3Bug/Tmprss11d^em3Bug Tmprss11e^em2Bug/Tmprss11e^em2Bug Tmprss11f^em3Bug/Tmprss11f^em3Bug Tmprss11g^em2Bug/Tmprss11g^em2Bug	FVB/NJ-Tmprss11c^em3Bug Tmprss11d^em3Bug Tmprss11a^em3Bug Tmprss11g^em2Bug Tmprss11f^em3Bug Tmprss11b^em2Bug Tmprss11e^em2Bug	MGI:6364585

Allelic Composition	Tmprss11a^em3Bug/Tmprss11a^em3Bug Tmprss11b^em2Bug/Tmprss11b^em2Bug Tmprss11c^em3Bug/Tmprss11c^em3Bug Tmprss11d^em3Bug/Tmprss11d^em3Bug Tmprss11e^em2Bug/Tmprss11e^em2Bug Tmprss11g^em2Bug/Tmprss11g^em2Bug
Genetic Background	FVB/NJ-Tmprss11c^em3Bug Tmprss11d^em3Bug Tmprss11a^em3Bug Tmprss11g^em2Bug Tmprss11b^em2Bug Tmprss11e^em2Bug

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tmprss11a^em3Bug mutation (0 available); any Tmprss11a mutation (29 available)
Tmprss11b^em2Bug mutation (0 available); any Tmprss11b mutation (25 available)
Tmprss11c^em3Bug mutation (0 available); any Tmprss11c mutation (37 available)
Tmprss11d^em3Bug mutation (0 available); any Tmprss11d mutation (34 available)
Tmprss11e^em2Bug mutation (0 available); any Tmprss11e mutation (26 available)
Tmprss11g^em2Bug mutation (0 available); any Tmprss11g mutation (30 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:279596 )

N	• mice exhibit normal transepidermal water loss in newborns

Allelic Composition	Tmprss11a^em3Bug/Tmprss11a^em3Bug Tmprss11b^em2Bug/Tmprss11b^em2Bug Tmprss11c^em3Bug/Tmprss11c^em3Bug Tmprss11d^em3Bug/Tmprss11d^em3Bug Tmprss11e^em2Bug/Tmprss11e^em2Bug Tmprss11f^em3Bug/Tmprss11f^em3Bug Tmprss11g^em2Bug/Tmprss11g^em2Bug
Genetic Background	FVB/NJ-Tmprss11c^em3Bug Tmprss11d^em3Bug Tmprss11a^em3Bug Tmprss11g^em2Bug Tmprss11f^em3Bug Tmprss11b^em2Bug Tmprss11e^em2Bug

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tmprss11a^em3Bug mutation (0 available); any Tmprss11a mutation (29 available)
Tmprss11b^em2Bug mutation (0 available); any Tmprss11b mutation (25 available)
Tmprss11c^em3Bug mutation (0 available); any Tmprss11c mutation (37 available)
Tmprss11d^em3Bug mutation (0 available); any Tmprss11d mutation (34 available)
Tmprss11e^em2Bug mutation (0 available); any Tmprss11e mutation (26 available)
Tmprss11f^em3Bug mutation (0 available); any Tmprss11f mutation (39 available)
Tmprss11g^em2Bug mutation (0 available); any Tmprss11g mutation (30 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

impaired skin barrier function ( J:279596 )

• in newborn mice

integument

impaired skin barrier function ( J:279596 )

• in newborn mice

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