About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Scml1tm1.2Atot
targeted mutation 1.2, Attila Toth
MGI:6362616
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Scml1tm1.2Atot/Scml1tm1.2Atot STOCK Scml1tm1.2Atot/Atot MGI:6362620
ot2
Scml1tm1.2Atot/Y STOCK Scml1tm1.2Atot/Atot MGI:6362621


Genotype
MGI:6362620
hm1
Allelic
Composition
Scml1tm1.2Atot/Scml1tm1.2Atot
Genetic
Background
STOCK Scml1tm1.2Atot/Atot
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• viable and fertile with no gross abnormalities




Genotype
MGI:6362621
ot2
Allelic
Composition
Scml1tm1.2Atot/Y
Genetic
Background
STOCK Scml1tm1.2Atot/Atot
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
N
• males are fertile
• no increase in apoptosis is seen in the seminiferous tubules
• no abnormalities in male meiosis, sex body formation or sex chromosome silencing are detected
• only a small minority of pachytene spermatocytes contain dense bodies unlike in controls and when present the dense bodies are never or rarely localized in or near sex bodies, respectively

cellular
• only a small minority of pachytene spermatocytes contain dense bodies unlike in controls and when present the dense bodies are never or rarely localized in or near sex bodies, respectively





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/07/2024
MGI 6.23
The Jackson Laboratory