All Phenotypes Pogz<tm1.2Jrk> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Pogz^tm1.2Jrk
targeted mutation 1.1, Jonathan R Keller
MGI:6360952

Summary

2 genotypes

Allelic Composition	Pogz^tm1.2Jrk/Pogz^tm1.2Jrk
Genetic Background	B6.129S1(Cg)-Pogz^tm1.2Jrk

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pogz^tm1.2Jrk mutation (0 available); any Pogz mutation (52 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• embryos rarely survive beyond E16.5

Allelic Composition	Pogz^tm1.2Jrk/Pogz^tm1.2Jrk
Genetic Background	involves: 129S1/Sv * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pogz^tm1.2Jrk mutation (0 available); any Pogz mutation (52 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• reduced survival observed at E15.5 through E18.5

• fewer than expected mice are present at E10.5

• no mice are present at weaning

liver/biliary system

liver hypoplasia ( J:271614 )

• at E15.5 with reduced erythroid, B and myeloid cell numbers without a reduction in frequency

growth/size/body

decreased fetal size ( J:271614 )

• at E15.5

hematopoietic system

anemia ( J:271614 )

• at E15.5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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