Phenotypes associated with this allele

• Allele Symbol: Cela1^em1Rjv
• Allele Name: endonuclease-mediated mutation 1, Rajiv L Joshi
• Allele ID: MGI:6359441
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cela1^em1Rjv/Cela1^em1Rjv	involves: C57BL/6	MGI:6359719

Genotype
MGI:6359719

hm1

• Allelic Composition: Cela1^em1Rjv/Cela1^em1Rjv
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

respiratory system

increased wet-to-dry lung weight ratio ( J:278574 )

abnormal pulmonary alveolar system morphology ( J:278574 )

• small airspace

• however, mice undergo alveolar septation

abnormal pulmonary elastic fiber morphology ( J:278574 )

• at P14, mice exhibit reduced elastase activity in distal airspace walls while elastin fibers are increased in airspace walls compared with wild-type mice

increased lung elastance ( J:278574 )