Phenotypes associated with this allele

• Allele Symbol: Pik3c2b^tm1.1Arte
• Allele Name: targeted mutation 1.1 TaconicArtemis
• Allele ID: MGI:6355464
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pik3c2b^tm1.1Arte/Pik3c2b^tm1.1Arte	involves: C57BL/6J * C57BL/6N	MGI:8394027

Genotype
MGI:8394027

hm1

• Allelic Composition: Pik3c2b^tm1.1Arte/Pik3c2b^tm1.1Arte
• Genetic Background: involves: C57BL/6J * C57BL/6N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:252034 )

N • normal food intake

embryo

embryo phenotype ( J:252034 )

N • mice born at expected Mendelian ratios

growth/size/body

growth/size/body region phenotype ( J:252034 )

N • normal growth and development

N • normal body weight gain after 16 weeks on HFD

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:252034 )

N • normal blood glucose levels under fed or fasted conditions

N • normal levels of circulating leptin, adiponectin, triglycerides, free fatty acids, and cholesterol Under randomly fed conditions

N • normal energy expenditure

decreased circulating insulin level ( J:252034 )

• in glucose and insulin tolerance tests after overnight fast

increased insulin sensitivity ( J:252034 )

• enhanced glucose tolerance in glucose and insulin tolerance tests after overnight fast

liver/biliary system

decreased susceptibility to diet-induced hepatic steatosis ( J:252034 )

• after 16 weeks on HFD

reproductive system

reproductive system phenotype ( J:252034 )

N • fertile