Phenotypes associated with this allele

• Allele Symbol: Stx4a^tm1.2Radac
• Allele Name: targeted mutation 1.2, Roberto Adachi
• Allele ID: MGI:6355366
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Stx4a^tm1.2Radac/Stx4a^tm1.2Radac	involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6J	MGI:7469805
ht2	Stx4a^tm1.2Radac/Stx4a^+	involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6J	MGI:7469806

Genotype
MGI:7469805

hm1

• Allelic Composition: Stx4a^tm1.2Radac/Stx4a^tm1.2Radac
• Genetic Background: involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

prenatal lethality, complete penetrance ( J:275367 )

• heterozygous intercrosses fail to produce homozygotes; reported as embryonic lethals but stage of lethality is not specified

Genotype
MGI:7469806

ht2

• Allelic Composition: Stx4a^tm1.2Radac/Stx4a⁺
• Genetic Background: involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6J

mortality/aging

mortality/aging ( J:275367 )

N • mice are viable, grossly normal, and exhibit a normal life span when raised in a specific pathogen-free facility

immune system

immune system phenotype ( J:275367 )

• mice exhibit no significant changes in the total number, distribution or structure of mast cells relative to wild-type controls