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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Stx4atm1.2Radac
targeted mutation 1.2, Roberto Adachi
MGI:6355366
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Stx4atm1.2Radac/Stx4atm1.2Radac involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6J MGI:7469805
ht2
 		Stx4atm1.2Radac/Stx4a+ involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6J MGI:7469806


Genotype
MGI:7469805
hm1
Allelic
Composition		 Stx4atm1.2Radac/Stx4atm1.2Radac
Genetic
Background		 involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stx4atm1.2Radac mutation (0 available); any Stx4a mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, complete penetrance ( J:275367 )
• heterozygous intercrosses fail to produce homozygotes; reported as embryonic lethals but stage of lethality is not specified




Genotype
MGI:7469806
ht2
Allelic
Composition		 Stx4atm1.2Radac/Stx4a+
Genetic
Background		 involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stx4atm1.2Radac mutation (0 available); any Stx4a mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
mortality/aging ( J:275367 )
N
• mice are viable, grossly normal, and exhibit a normal life span when raised in a specific pathogen-free facility

immune system
immune system phenotype ( J:275367 )
• mice exhibit no significant changes in the total number, distribution or structure of mast cells relative to wild-type controls




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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory