All Phenotypes Tg(Thy1-APP*)2Tbay MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(Thy1-APP*)2Tbay
transgene insertion 2, Thomas A Bayer
MGI:6343355

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
tg1	Tg(Thy1-APP*)2Tbay/0	C57BL/6J-Tg(Thy1-APP*)2Tbay	MGI:6392258

Allelic Composition	Tg(Thy1-APP*)2Tbay/0
Genetic Background	C57BL/6J-Tg(Thy1-APP*)2Tbay

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Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

abnormal spatial reference memory ( J:275188 )

nervous system

loss of hippocampal neurons ( J:275188 )

• age-dependent neuron loss was seen in the hippocampus CA1 region

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Alzheimer's disease		DOID:10652		J:275188

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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