Analysis Tools
reproductive system
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• no accessory structures are seen in spermatozoa, suggesting impaired formation of outer dense fibers, the mitochondrial sheath and the fibrous sheath
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• shortened flagella
• however, the 9 + 2 structure of the axoneme including the outer arm dynein is intact in spermatozoa
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• spermatozoa from the cauda epididymis show severe defects in sperm heads
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• no motile spermatozoa are seen
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• spermatids show impaired development of flagella, lacking elongating flagella, although they have a developing acrosome
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• males are infertile, producing no litters when mated with wild-type females
• however, spermatozoa can activate oocytes with intracytoplasmic sperm injection
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cellular
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• no accessory structures are seen in spermatozoa, suggesting impaired formation of outer dense fibers, the mitochondrial sheath and the fibrous sheath
|
|
|
• shortened flagella
• however, the 9 + 2 structure of the axoneme including the outer arm dynein is intact in spermatozoa
|
|
|
• spermatozoa from the cauda epididymis show severe defects in sperm heads
|
|
|
• no motile spermatozoa are seen
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