Phenotypes associated with this allele

• Allele Symbol: Emsy^{em1(IMPC)Ccpcz}
• Allele Name: endonuclease-mediated mutation 1, Institute of Molecular Genetics
• Allele ID: MGI:6341933
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Emsy^em1(IMPC)Ccpcz/Emsy^em1(IMPC)Ccpcz	C57BL/6NCrl-Emsy^em1(IMPC)Ccpcz/Ccpcz	MGI:7471987
ht2	Emsy^em1(IMPC)Ccpcz/Emsy^+	C57BL/6NCrl-Emsy^em1(IMPC)Ccpcz/Ccpcz	MGI:7471986

Genotype
MGI:7471987

hm1

• Allelic Composition: Emsy^{em1(IMPC)Ccpcz}/Emsy^{em1(IMPC)Ccpcz}
• Genetic Background: C57BL/6NCrl-Emsy^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Emsy

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal heart morphology ( J:211773 )

IMPC - CCP-IMG

abnormal heart looping ( J:211773 )

IMPC - CCP-IMG

craniofacial

abnormal pharyngeal arch morphology ( J:211773 )

IMPC - CCP-IMG

embryo

abnormal pharyngeal arch morphology ( J:211773 )

IMPC - CCP-IMG

abnormal embryo development ( J:211773 )

IMPC - CCP-IMG

embryonic growth retardation ( J:211773 )

IMPC - CCP-IMG

abnormal embryo size ( J:211773 )

IMPC - CCP-IMG

abnormal limb bud morphology ( J:211773 )

IMPC - CCP-IMG

abnormal neural tube morphology ( J:211773 )

IMPC - CCP-IMG

abnormal neural tube closure ( J:211773 )

IMPC - CCP-IMG

abnormal somite shape ( J:211773 )

IMPC - CCP-IMG

abnormal tail bud morphology ( J:211773 )

IMPC - CCP-IMG

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - CCP-IMG

abnormal embryo size ( J:211773 )

IMPC - CCP-IMG

hearing/vestibular/ear

abnormal otic vesicle morphology ( J:211773 )

IMPC - CCP-IMG

limbs/digits/tail

abnormal limb bud morphology ( J:211773 )

IMPC - CCP-IMG

abnormal tail bud morphology ( J:211773 )

IMPC - CCP-IMG

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - CCP-IMG

preweaning lethality, complete penetrance ( J:211773 )

IMPC - CCP-IMG

nervous system

abnormal neural tube morphology ( J:211773 )

IMPC - CCP-IMG

abnormal neural tube closure ( J:211773 )

IMPC - CCP-IMG

abnormal forebrain development ( J:211773 )

IMPC - CCP-IMG

abnormal hindbrain development ( J:211773 )

IMPC - CCP-IMG

abnormal midbrain development ( J:211773 )

IMPC - CCP-IMG

vision/eye

abnormal optic vesicle formation ( J:211773 )

IMPC - CCP-IMG

Genotype
MGI:7471986

ht2

• Allelic Composition: Emsy^{em1(IMPC)Ccpcz}/Emsy⁺
• Genetic Background: C57BL/6NCrl-Emsy^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Emsy

cardiovascular system

abnormal heart morphology ( J:211773 )

♂

IMPC - CCP-IMG

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

endocrine/exocrine glands

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - CCP-IMG

small seminal vesicle ( J:211773 )

♂

IMPC - CCP-IMG

abnormal testis morphology ( J:211773 )

♂

IMPC - CCP-IMG

enlarged testis ( J:211773 )

♂

IMPC - CCP-IMG

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

hematopoietic system

decreased hemoglobin content ( J:211773 )

♀

IMPC - CCP-IMG

increased red blood cell distribution width ( J:211773 )

IMPC - CCP-IMG

increased NK cell number ( J:211773 )

♂

IMPC - CCP-IMG

homeostasis/metabolism

impaired glucose tolerance ( J:211773 )

♀

IMPC - CCP-IMG

immune system

increased NK cell number ( J:211773 )

♂

IMPC - CCP-IMG

limbs/digits/tail

short tibia ( J:211773 )

♂

IMPC - CCP-IMG

renal/urinary system

abnormal kidney morphology ( J:211773 )

IMPC - CCP-IMG

reproductive system

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - CCP-IMG

small seminal vesicle ( J:211773 )

♂

IMPC - CCP-IMG

abnormal testis morphology ( J:211773 )

♂

IMPC - CCP-IMG

enlarged testis ( J:211773 )

♂

IMPC - CCP-IMG

abnormal epididymis morphology ( J:211773 )

♂

IMPC - CCP-IMG

enlarged epididymis ( J:211773 )

♂

IMPC - CCP-IMG

skeleton

short tibia ( J:211773 )

♂

IMPC - CCP-IMG

vertebral transformation ( J:211773 )

IMPC - CCP-IMG