Phenotypes associated with this allele

• Allele Symbol: Insig1^{em1(IMPC)Ccpcz}
• Allele Name: endonuclease-mediated mutation 1, Institute of Molecular Genetics
• Allele ID: MGI:6341860
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Insig1^em1(IMPC)Ccpcz/Insig1^em1(IMPC)Ccpcz	C57BL/6N-Insig1^em1(IMPC)Ccpcz/Ccpcz	MGI:6492895

Genotype
MGI:6492895

hm1

• Allelic Composition: Insig1^{em1(IMPC)Ccpcz}/Insig1^{em1(IMPC)Ccpcz}
• Genetic Background: C57BL/6N-Insig1^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Insig1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

increased aggression ( J:211773 )

♀

IMPC - CCP-IMG

increased freezing behavior ( J:211773 )

♂

IMPC - CCP-IMG

decreased locomotor activity ( J:211773 )

IMPC - CCP-IMG

craniofacial

abnormal maxilla morphology ( J:211773 )

IMPC - CCP-IMG

growth/size/body

abnormal maxilla morphology ( J:211773 )

IMPC - CCP-IMG

decreased body weight ( J:211773 )

♀

IMPC - CCP-IMG

hematopoietic system

increased mean corpuscular hemoglobin ( J:211773 )

IMPC - CCP-IMG

homeostasis/metabolism

increased fasting circulating glucose level ( J:211773 )

IMPC - CCP-IMG

impaired glucose tolerance ( J:211773 )

♀

IMPC - CCP-IMG

decreased circulating chloride level ( J:211773 )

IMPC - CCP-IMG

abnormal cholesterol homeostasis ( J:211773 )

♀

IMPC - CCP-IMG

renal/urinary system

abnormal urinary bladder morphology ( J:211773 )

♀

IMPC - CCP-IMG

skeleton

abnormal maxilla morphology ( J:211773 )

IMPC - CCP-IMG

vision/eye

abnormal retina morphology ( J:211773 )

IMPC - CCP-IMG