Phenotypes associated with this allele

• Allele Symbol: Zg16^em1(IMPC)Ics
• Allele Name: endonuclease-mediated mutation 1, Mouse Clinical Institute
• Allele ID: MGI:6336099
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Zg16^em1(IMPC)Ics/Zg16^+	C57BL/6N-Zg16^em1(IMPC)Ics/Ics	MGI:8209536

Genotype
MGI:8209536

ht1

• Allelic Composition: Zg16^em1(IMPC)Ics/Zg16⁺
• Genetic Background: C57BL/6N-Zg16^em1(IMPC)Ics/Ics

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

increased brain size ( J:343325 )

• in adult males and females, the total brain area is increased by 7% relative to wild-type controls

abnormal hippocampal commissure morphology ( J:343325 )

♂ • in adult males, the area of the dorsal hippocampal commissure is enlarged by 44% relative to wild-type males

increased anterior commissure size ( J:343325 )

♂ • in adult males, the area of the anterior commissure-anterior part is increased in size by 26% relative to wild-type males

increased habenula size ( J:343325 )

♂ • in adult males, the area of the habenular nucleus is increased by 10% relative to wild-type males

abnormal arcuate nucleus of hypothalamus morphology ( J:343325 )

♂ • in adult males, the area of the arcuate nucleus is increased by 37% relative to wild-type males

increased hippocampal fimbria size ( J:343325 )

♂ • in adult males, the area of the hippocampal fimbria is increased by 13% relative to wild-type males

increased piriform cortex size ( J:343325 )

♂ • in adult males, the area of the piriform cortex is increased by 21% relative to wild-type males