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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ppp4cem1(IMPC)Ics
endonuclease-mediated mutation 1, Mouse Clinical Institute
MGI:6336089
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Ppp4cem1(IMPC)Ics/Ppp4c+ C57BL/6N-Ppp4cem1(IMPC)Ics/Ics MGI:6408586


Genotype
MGI:6408586
ht1
Allelic
Composition
Ppp4cem1(IMPC)Ics/Ppp4c+
Genetic
Background
C57BL/6N-Ppp4cem1(IMPC)Ics/Ics
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppp4cem1(IMPC)Ics mutation (1 available); any Ppp4c mutation (41 available)
Data Sources
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological

cardiovascular system

growth/size/body

homeostasis/metabolism

nervous system
• in adult males, total brain area is reduced by 10% at bregma +0.98 mm and by 7% at bregma -1.34 mm relative to wild-type males
• in adult males, the area of the genu of the corpus callosum is reduced by 16% while the width of the genu of the corpus callosum is reduced by 9% relative to wild-type males
• in adult females, the height of the genu of the corpus callosum is reduced by 8% relative to wild-type females
• in adult males, the area of the anterior commissure-anterior part is reduced by 12% relative to wild-type males
• in adult males, the area of the caudate putamen is reduced by 10% relative to wild-type males
• in adult males, the area of the retrosplenial granular cortex is reduced by 9% relative to wild-type males
• in adult males, the height of the cingulate cortex is reduced by 7% relative to wild-type males
• in adult males, the height of the somatosensory cortex is reduced by 10% at bregma +0.98 mm and by 3% at bregma -1.34 mm relative to wild-type males





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory