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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Chrdl1em1Nja
endonuclease-mediated mutation 1, Nicola J Allen
MGI:6315865
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ot1
 		Chrdl1em1Nja/Y involves: C57BL/6J * DBA/2J MGI:6315867


Genotype
MGI:6315867
ot1
Allelic
Composition		 Chrdl1em1Nja/Y
Genetic
Background		 involves: C57BL/6J * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Chrdl1em1Nja mutation (0 available); any Chrdl1 mutation (13 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal synapse morphology ( J:269376 )
• altered properties with less glutamate receptors
abnormal synaptic plasticity ( J:269376 )
• increased in the visual cortex
abnormal miniature excitatory postsynaptic currents ( J:269376 )
• increased decay time, rise time and charge transfer
• however, frequency and amplitude are normal




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory