Phenotypes associated with this allele

• Allele Symbol: Klhl6^M8Btlr
• Allele Name: mutation 8, Bruce Beutler
• Allele ID: MGI:6305808
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Klhl6^M8Btlr/Klhl6^M8Btlr	C57BL/6J-Klhl6^M8Btlr	MGI:6305812

Genotype
MGI:6305812

hm1

• Allelic Composition: Klhl6^M8Btlr/Klhl6^M8Btlr
• Genetic Background: C57BL/6J-Klhl6^M8Btlr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

decreased B cell number ( J:274963 )

• reduced frequencies of B cells, IgD+ B cells, and IgM+ B cells in the peripheral blood

• reduced peripheral blood B to T cell ratios

increased T cell number ( J:274963 )

• increased frequencies of T cells in the peripheral blood

• reduced peripheral blood B to T cell ratios

increased CD4-positive, alpha-beta T cell number ( J:274963 )

• increased frequencies of CD4+ T cells in the peripheral blood

hematopoietic system

decreased B cell number ( J:274963 )

• reduced frequencies of B cells, IgD+ B cells, and IgM+ B cells in the peripheral blood

• reduced peripheral blood B to T cell ratios

increased T cell number ( J:274963 )

• increased frequencies of T cells in the peripheral blood

• reduced peripheral blood B to T cell ratios

increased CD4-positive, alpha-beta T cell number ( J:274963 )

• increased frequencies of CD4+ T cells in the peripheral blood