Phenotypes associated with this allele

• Allele Symbol: Taok2^{tm1b(EUCOMM)Hmgu}
• Allele Name: targeted mutation 1b, Helmholtz Zentrum Muenchen GmbH
• Allele ID: MGI:6305716
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Taok2^tm1b(EUCOMM)Hmgu/Taok2^+	C57BL/6N-Taok2^tm1b(EUCOMM)Hmgu/Ics	MGI:6480601

Genotype
MGI:6480601

ht1

• Allelic Composition: Taok2^{tm1b(EUCOMM)Hmgu}/Taok2⁺
• Genetic Background: C57BL/6N-Taok2^{tm1b(EUCOMM)Hmgu}/Ics
• Cell Lines: HEPD0565_3_D01

Data Sources

IMPC Data for Taok2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased circulating alkaline phosphatase level ( J:211773 )

♂

IMPC - ICS

nervous system

increased brain size ( J:343325 )

♂ • in adult males, the total brain area is enlarged by 6% relative to wild-type males

increased corpus callosum size ( J:343325 )

♂ • in adult males, the height of the genu of the corpus callosum is increased by 27% relative to wild-type males

abnormal hippocampal commissure morphology ( J:343325 )

♂ • in adult males, the area of the dorsal hippocampal commissure is reduced by 15% relative to wild-type males

decreased anterior commissure size ( J:343325 )

♂ • in adult males, the area of the anterior commissure-anterior part is smaller by 17% relative to wild-type males

increased cingulate cortex size ( J:343325 )

♂ • in adult males, the area of the cingulate cortex is enlarged by 9% relative to wild-type males

decreased primary motor cortex size ( J:343325 )

♂ • in adult males, the height of the primary motor cortex is smaller by 8% relative to wild-type males