All Phenotypes Prkcb<M5Btlr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Prkcb^M5Btlr
mutation 5, Bruce Beutler
MGI:6305128

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Prkcb^M5Btlr/Prkcb^M5Btlr	C57BL/6J-Prkcb^M5Btlr	MGI:6305148

Allelic Composition	Prkcb^M5Btlr/Prkcb^M5Btlr
Genetic Background	C57BL/6J-Prkcb^M5Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prkcb^M5Btlr mutation (0 available); any Prkcb mutation (37 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased IgM level ( J:274861 )

• diminished T-independent antibody response to 4-hydroxy-3-nitrophenylacetyl-Ficoll (NP-Ficoll)

impaired humoral immune response ( J:274861 )

• diminished T-independent antibody response to 4-hydroxy-3-nitrophenylacetyl-Ficoll (NP-Ficoll)

hematopoietic system

decreased IgM level ( J:274861 )

• diminished T-independent antibody response to 4-hydroxy-3-nitrophenylacetyl-Ficoll (NP-Ficoll)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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