Phenotypes associated with this allele

• Allele Symbol: Vldlr^rnv4
• Allele Name: retinal neovascularization 4
• Allele ID: MGI:6295987
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Vldlr^rnv4/Vldlr^rnv4	B6;BKS-Vldlr^rnv4/BocJ	MGI:6296604

Genotype
MGI:6296604

hm1

• Allelic Composition: Vldlr^rnv4/Vldlr^rnv4
• Genetic Background: B6;BKS-Vldlr^rnv4/BocJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal retina vasculature morphology ( J:274099 )

• subretinal vascularization by 14 days of age with pink-grey retinal lesions visible by indirect ophthalmoscopy

abnormal retina blood vessel pattern ( J:274099 )

abnormal cone electrophysiology ( J:274099 )

• delayed cone ERG response is found by 1 month of age

abnormal rod electrophysiology ( J:274099 )

• progressive loss of rod ERG with decrease evident at 1 month of age

cardiovascular system

abnormal retina vasculature morphology ( J:274099 )

• subretinal vascularization by 14 days of age with pink-grey retinal lesions visible by indirect ophthalmoscopy

abnormal retina blood vessel pattern ( J:274099 )

growth/size/body

decreased body size ( J:274099 )

• young mice are smaller than normal, but catch up to C57BL/6J controls by approximately a month of age

integument

alopecia ( J:274099 )

• homozygotes have patchy hair loss at wean age, but the fur grows back