About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pappam1Btlr
mutation 1, Bruce Beutler
MGI:6286271
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pappam1Btlr/Pappam1Btlr C57BL/6J-Pappam1Btlr MGI:6286273
hm2
 		Pappam1Btlr/Pappam1Btlr C57BL/6J-Pappam1Btlr/Btlr MGI:6761525


Genotype
MGI:6286273
hm1
Allelic
Composition		 Pappam1Btlr/Pappam1Btlr
Genetic
Background		 C57BL/6J-Pappam1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pappam1Btlr mutation (0 available); any Pappa mutation (71 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
decreased bone mineral content ( J:272859 )
• in the tibia and femur
decreased bone mineral density ( J:272859 )
• in the tibia and femur

growth/size/body
decreased lean body mass ( J:272859 )
decreased body weight ( J:272859 )




Genotype
MGI:6761525
hm2
Allelic
Composition		 Pappam1Btlr/Pappam1Btlr
Genetic
Background		 C57BL/6J-Pappam1Btlr/Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pappam1Btlr mutation (0 available); any Pappa mutation (71 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
limbs/digits/tail

skeleton
decreased bone mineral density ( J:309727 )
• in the tibia and femur




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory