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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pi4kam2Btlr
mutation 2, Bruce Beutler
MGI:6286120
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Pi4kam2Btlr/Pi4kam2Btlr C57BL/6J-Pi4kam2Btlr MGI:6286122


Genotype
MGI:6286122
hm1
Allelic
Composition		 Pi4kam2Btlr/Pi4kam2Btlr
Genetic
Background		 C57BL/6J-Pi4kam2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pi4kam2Btlr mutation (0 available); any Pi4ka mutation (129 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased alpha-beta T cell number ( J:272852 )
• increased frequencies of CD44+ T cells in the peripheral blood
increased CD4-positive, alpha-beta T cell number ( J:272852 )
• increased frequencies of CD44+ CD4+ T cells in the peripheral blood
increased central memory CD4-positive, alpha-beta T cell number ( J:272852 )
• increased frequencies of central memory CD4 T cells in CD4 T cellsin the peripheral blood

hematopoietic system
increased alpha-beta T cell number ( J:272852 )
• increased frequencies of CD44+ T cells in the peripheral blood
increased CD4-positive, alpha-beta T cell number ( J:272852 )
• increased frequencies of CD44+ CD4+ T cells in the peripheral blood
increased central memory CD4-positive, alpha-beta T cell number ( J:272852 )
• increased frequencies of central memory CD4 T cells in CD4 T cellsin the peripheral blood




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory