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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Itgamm3Btlr
mutation 3, Bruce Beutler
MGI:6285549
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Itgamm3Btlr/Itgamm3Btlr C57BL/6J-Itgamm3Btlr MGI:6285555


Genotype
MGI:6285555
hm1
Allelic
Composition		 Itgamm3Btlr/Itgamm3Btlr
Genetic
Background		 C57BL/6J-Itgamm3Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itgamm3Btlr mutation (0 available); any Itgam mutation (49 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased CD11b-high dendritic cell number ( J:272533 )
• reduced frequency of CD11b+dendritic cells (DCs) gated in CD11c+cells in the peripheral blood

immune system
decreased CD11b-high dendritic cell number ( J:272533 )
• reduced frequency of CD11b+dendritic cells (DCs) gated in CD11c+cells in the peripheral blood




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory