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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dock8M2Btlr
mutation 2, Bruce Beutler
MGI:6285537
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dock8M2Btlr/Dock8M2Btlr C57BL/6J-Dock8M2Btlr MGI:6285539


Genotype
MGI:6285539
hm1
Allelic
Composition		 Dock8M2Btlr/Dock8M2Btlr
Genetic
Background		 C57BL/6J-Dock8M2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dock8M2Btlr mutation (0 available); any Dock8 mutation (101 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased CD8-positive, alpha-beta T cell number ( J:272530 )
• reduced CD8+ T cell frequencies in the peripheral blood

immune system
decreased CD8-positive, alpha-beta T cell number ( J:272530 )
• reduced CD8+ T cell frequencies in the peripheral blood




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory