About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dock8M2Btlr
mutation 2, Bruce Beutler
MGI:6285537
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dock8M2Btlr/Dock8M2Btlr C57BL/6J-Dock8M2Btlr MGI:6285539


Genotype
MGI:6285539
hm1
Allelic
Composition		 Dock8M2Btlr/Dock8M2Btlr
Genetic
Background		 C57BL/6J-Dock8M2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dock8M2Btlr mutation (0 available); any Dock8 mutation (103 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased CD8-positive, alpha-beta T cell number ( J:272530 )
• reduced CD8+ T cell frequencies in the peripheral blood

immune system
decreased CD8-positive, alpha-beta T cell number ( J:272530 )
• reduced CD8+ T cell frequencies in the peripheral blood




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory