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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		PrkdcM16Btlr
mutation 16, Bruce Beutler
MGI:6285484
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		PrkdcM16Btlr/PrkdcM16Btlr C57BL/6J-PrkdcM16Btlr MGI:6285486


Genotype
MGI:6285486
hm1
Allelic
Composition		 PrkdcM16Btlr/PrkdcM16Btlr
Genetic
Background		 C57BL/6J-PrkdcM16Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
PrkdcM16Btlr mutation (0 available); any Prkdc mutation (399 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal CD8-positive, alpha-beta T cell differentiation ( J:272520 )
• increased CD44 expression on peripheral blood CD8 T cells

immune system
abnormal CD8-positive, alpha-beta T cell differentiation ( J:272520 )
• increased CD44 expression on peripheral blood CD8 T cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory