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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Prkdcm14Btlr
mutation 14, Bruce Beutler
MGI:6285200
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Prkdcm14Btlr/Prkdcm14Btlr C57BL/6J-Prkdcm14Btlr MGI:6285206


Genotype
MGI:6285206
hm1
Allelic
Composition		 Prkdcm14Btlr/Prkdcm14Btlr
Genetic
Background		 C57BL/6J-Prkdcm14Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prkdcm14Btlr mutation (0 available); any Prkdc mutation (399 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal CD4-positive T cell differentiation ( J:272442 )
• increased CD44 expression on peripheral blood CD4 T cells

growth/size/body
increased body weight ( J:272442 )
• increased body weights compared to wild-type littermates

hematopoietic system
abnormal CD4-positive T cell differentiation ( J:272442 )
• increased CD44 expression on peripheral blood CD4 T cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory