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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ptpn6m6Btlr
mutation 6, Bruce Beutler
MGI:6285167
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ptpn6m6Btlr/Ptpn6m6Btlr C57BL/6J-Ptpn6m6Btlr MGI:6285169


Genotype
MGI:6285169
hm1
Allelic
Composition		 Ptpn6m6Btlr/Ptpn6m6Btlr
Genetic
Background		 C57BL/6J-Ptpn6m6Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptpn6m6Btlr mutation (0 available); any Ptpn6 mutation (47 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal T cell differentiation ( J:272439 )
• increased CD44 expression on peripheral blood T cells
abnormal CD8-positive, alpha-beta T cell differentiation ( J:272439 )
• increased CD44 expression on CD8+ T cells

hematopoietic system
abnormal T cell differentiation ( J:272439 )
• increased CD44 expression on peripheral blood T cells
abnormal CD8-positive, alpha-beta T cell differentiation ( J:272439 )
• increased CD44 expression on CD8+ T cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory