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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dock2M12Btlr
mutation 12, Bruce Beutler
MGI:6284854
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dock2M12Btlr/Dock2M12Btlr C57BL/6J-Dock2M12Btlr MGI:6284856


Genotype
MGI:6284856
hm1
Allelic
Composition		 Dock2M12Btlr/Dock2M12Btlr
Genetic
Background		 C57BL/6J-Dock2M12Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dock2M12Btlr mutation (0 available); any Dock2 mutation (144 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased B-1a cell number ( J:272406 )
• reduced frequencies of B1a cells in B1 cells in the peripheral blood

immune system
decreased B-1a cell number ( J:272406 )
• reduced frequencies of B1a cells in B1 cells in the peripheral blood




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory