About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dock2m10Btlr
mutation 10, Bruce Beutler
MGI:6284832
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dock2m10Btlr/Dock2m10Btlr C57BL/6J-Dock2m10Btlr MGI:6284834


Genotype
MGI:6284834
hm1
Allelic
Composition		 Dock2m10Btlr/Dock2m10Btlr
Genetic
Background		 C57BL/6J-Dock2m10Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dock2m10Btlr mutation (0 available); any Dock2 mutation (144 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased B-1b cell number ( J:272404 )
• reduced frequencies of B1b cells in the peripheral blood
increased NK cell number ( J:272404 )
• increased frequencies of NK cells in the peripheral blood

immune system
decreased B-1b cell number ( J:272404 )
• reduced frequencies of B1b cells in the peripheral blood
increased NK cell number ( J:272404 )
• increased frequencies of NK cells in the peripheral blood




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory