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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Jak3M7Btlr
mutation 7, Bruce Beutler
MGI:6284812
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Jak3M7Btlr/Jak3M7Btlr C57BL/6J-Jak3M7Btlr MGI:6284814


Genotype
MGI:6284814
hm1
Allelic
Composition		 Jak3M7Btlr/Jak3M7Btlr
Genetic
Background		 C57BL/6J-Jak3M7Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Jak3M7Btlr mutation (0 available); any Jak3 mutation (85 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal CD4-positive T cell differentiation ( J:272401 )
• increased expression of CD44 on peripheral blood CD4 T cells

immune system
abnormal CD4-positive T cell differentiation ( J:272401 )
• increased expression of CD44 on peripheral blood CD4 T cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory