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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dsg2m3Btlr
mutation 3, Bruce Beutler
MGI:6283582
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dsg2m3Btlr/Dsg2m3Btlr C57BL/6J-Dsg2m3Btlr MGI:6283584


Genotype
MGI:6283584
hm1
Allelic
Composition		 Dsg2m3Btlr/Dsg2m3Btlr
Genetic
Background		 C57BL/6J-Dsg2m3Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dsg2m3Btlr mutation (0 available); any Dsg2 mutation (84 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
increased susceptibility to induced colitis ( J:271977 )
• increased sensitivity to dextran sulfate sodium (DSS)-induced colitis at 10 days after DSS treatment

immune system
increased susceptibility to induced colitis ( J:271977 )
• increased sensitivity to dextran sulfate sodium (DSS)-induced colitis at 10 days after DSS treatment




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory