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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mpeg1tm1Pod
targeted mutation 1, Eckhard Podack
MGI:6281023
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Mpeg1tm1Pod/Mpeg1tm1Pod 129X1/SvJ-Mpeg1tm1Pod MGI:6281030
hm2
 		Mpeg1tm1Pod/Mpeg1tm1Pod involves: 129X1/SvJ * C57BL/6 MGI:6281027
ht3
 		Mpeg1tm1Pod/Mpeg1+ 129X1/SvJ-Mpeg1tm1Pod MGI:6281029
ht4
 		Mpeg1tm1Pod/Mpeg1+ involves: 129X1/SvJ * C57BL/6 MGI:6281026


Genotype
MGI:6281030
hm1
Allelic
Composition		 Mpeg1tm1Pod/Mpeg1tm1Pod
Genetic
Background		 129X1/SvJ-Mpeg1tm1Pod
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mpeg1tm1Pod mutation (0 available); any Mpeg1 mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
abnormal susceptibility to infection induced morbidity/mortality ( J:269474 )
• in mice inoculated with an isogenic cif::aadA or wild-type version of Y. pseudotuberculosis unlike mice on a mixed background

immune system
abnormal susceptibility to infection induced morbidity/mortality ( J:269474 )
• in mice inoculated with an isogenic cif::aadA or wild-type version of Y. pseudotuberculosis unlike mice on a mixed background




Genotype
MGI:6281027
hm2
Allelic
Composition		 Mpeg1tm1Pod/Mpeg1tm1Pod
Genetic
Background		 involves: 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mpeg1tm1Pod mutation (0 available); any Mpeg1 mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
abnormal susceptibility to infection induced morbidity/mortality ( J:269474 )
• in mice inoculated with an isogenic cif::aadA or wild-type version of Y. pseudotuberculosis

immune system
abnormal susceptibility to infection induced morbidity/mortality ( J:269474 )
• in mice inoculated with an isogenic cif::aadA or wild-type version of Y. pseudotuberculosis




Genotype
MGI:6281029
ht3
Allelic
Composition		 Mpeg1tm1Pod/Mpeg1+
Genetic
Background		 129X1/SvJ-Mpeg1tm1Pod
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mpeg1tm1Pod mutation (0 available); any Mpeg1 mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
abnormal susceptibility to infection induced morbidity/mortality ( J:269474 )
• in mice inoculated with an isogenic cif::aadA of Y. pseudotuberculosis
• however, response to wild-type Y. pseudotuberculosis is normal

immune system
abnormal susceptibility to infection induced morbidity/mortality ( J:269474 )
• in mice inoculated with an isogenic cif::aadA of Y. pseudotuberculosis
• however, response to wild-type Y. pseudotuberculosis is normal




Genotype
MGI:6281026
ht4
Allelic
Composition		 Mpeg1tm1Pod/Mpeg1+
Genetic
Background		 involves: 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mpeg1tm1Pod mutation (0 available); any Mpeg1 mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
abnormal susceptibility to infection induced morbidity/mortality ( J:269474 )
• in mice inoculated with an isogenic cif::aadA of Y. pseudotuberculosis
• however, response to wild-type Y. pseudotuberculosis is normal

immune system
abnormal susceptibility to infection induced morbidity/mortality ( J:269474 )
• in mice inoculated with an isogenic cif::aadA of Y. pseudotuberculosis
• however, response to wild-type Y. pseudotuberculosis is normal




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory