Phenotypes associated with this allele

• Allele Symbol: Drgx^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6276984
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Drgx^em1(IMPC)Mbp/Drgx^em1(IMPC)Mbp	C57BL/6N-Drgx^em1(IMPC)Mbp/MbpMmucd	MGI:6408597
ht2	Drgx^em1(IMPC)Mbp/Drgx^+	C57BL/6N-Drgx^em1(IMPC)Mbp/MbpMmucd	MGI:6408596

Genotype
MGI:6408597

hm1

• Allelic Composition: Drgx^em1(IMPC)Mbp/Drgx^em1(IMPC)Mbp
• Genetic Background: C57BL/6N-Drgx^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Drgx

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

embryonic growth retardation ( J:211773 )

♂

IMPC - UCD

growth/size/body

embryonic growth retardation ( J:211773 )

♂

IMPC - UCD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

♀

IMPC - UCD

preweaning lethality, incomplete penetrance ( J:211773 )

IMPC - UCD

Genotype
MGI:6408596

ht2

• Allelic Composition: Drgx^em1(IMPC)Mbp/Drgx⁺
• Genetic Background: C57BL/6N-Drgx^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Drgx

cardiovascular system

abnormal heart morphology ( J:211773 )

♀

IMPC - UCD

enlarged heart ( J:211773 )

♀

IMPC - UCD

endocrine/exocrine glands

abnormal adrenal gland morphology ( J:211773 )

♀

IMPC - UCD

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - UCD

abnormal testis morphology ( J:211773 )

♂

IMPC - UCD

enlarged testis ( J:211773 )

♂

IMPC - UCD

growth/size/body

enlarged heart ( J:211773 )

♀

IMPC - UCD

enlarged spleen ( J:211773 )

IMPC - UCD

hematopoietic system

abnormal spleen morphology ( J:211773 )

IMPC - UCD

enlarged spleen ( J:211773 )

IMPC - UCD

immune system

abnormal spleen morphology ( J:211773 )

IMPC - UCD

enlarged spleen ( J:211773 )

IMPC - UCD

abnormal lymph node morphology ( J:211773 )

♀

IMPC - UCD

enlarged lymph nodes ( J:211773 )

♀

IMPC - UCD

integument

abnormal skin morphology ( J:211773 )

♀

IMPC - UCD

liver/biliary system

abnormal liver morphology ( J:211773 )

♂

IMPC - UCD

renal/urinary system

abnormal kidney morphology ( J:211773 )

♀

IMPC - UCD

small kidney ( J:211773 )

♀

IMPC - UCD

reproductive system

abnormal seminal vesicle morphology ( J:211773 )

♂

IMPC - UCD

abnormal testis morphology ( J:211773 )

♂

IMPC - UCD

enlarged testis ( J:211773 )

♂

IMPC - UCD

abnormal uterus morphology ( J:211773 )

♀

IMPC - UCD

vision/eye

abnormal vitreous body morphology ( J:211773 )

IMPC - UCD