Phenotypes associated with this allele

• Allele Symbol: Dsp^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6276974
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dsp^em1(IMPC)Mbp/Dsp^em1(IMPC)Mbp	C57BL/6N-Dsp^em1(IMPC)Mbp/MbpMmucd	MGI:6408345
ht2	Dsp^em1(IMPC)Mbp/Dsp^+	C57BL/6N-Dsp^em1(IMPC)Mbp/MbpMmucd	MGI:6461222

Genotype
MGI:6408345

hm1

• Allelic Composition: Dsp^em1(IMPC)Mbp/Dsp^em1(IMPC)Mbp
• Genetic Background: C57BL/6N-Dsp^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Dsp

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal heart morphology ( J:211773 )

♀

IMPC - UCD

craniofacial

abnormal pharyngeal arch morphology ( J:211773 )

♀

IMPC - UCD

embryo

abnormal pharyngeal arch morphology ( J:211773 )

♀

IMPC - UCD

abnormal embryo turning ( J:211773 )

♀

IMPC - UCD

abnormal neural tube morphology ( J:211773 )

IMPC - UCD

mortality/aging

prenatal lethality prior to heart atrial septation ( J:211773 )

IMPC - UCD

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

nervous system

abnormal neural tube morphology ( J:211773 )

IMPC - UCD

abnormal midbrain development ( J:211773 )

♀

IMPC - UCD

Genotype
MGI:6461222

ht2

• Allelic Composition: Dsp^em1(IMPC)Mbp/Dsp⁺
• Genetic Background: C57BL/6N-Dsp^em1(IMPC)Mbp/MbpMmucd

Data Sources

IMPC Data for Dsp

embryo

abnormal embryo turning ( J:211773 )

IMPC - UCD

abnormal neural tube morphology ( J:211773 )

IMPC - UCD

abnormal neural tube closure ( J:211773 )

IMPC - UCD

abnormal placenta morphology ( J:211773 )

♂

IMPC - UCD

immune system

abnormal lymph node morphology ( J:211773 )

IMPC - UCD

enlarged lymph nodes ( J:211773 )

IMPC - UCD

nervous system

abnormal neural tube morphology ( J:211773 )

IMPC - UCD

abnormal neural tube closure ( J:211773 )

IMPC - UCD