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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Dhcr7em1(IMPC)Mbp
endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
MGI:6276960
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Dhcr7em1(IMPC)Mbp/Dhcr7em1(IMPC)Mbp C57BL/6N-Dhcr7em1(IMPC)Mbp/MbpMmucd MGI:6408338
ht2
 		Dhcr7em1(IMPC)Mbp/Dhcr7+ C57BL/6N-Dhcr7em1(IMPC)Mbp/MbpMmucd MGI:6461205


Genotype
MGI:6408338
hm1
Allelic
Composition		 Dhcr7em1(IMPC)Mbp/Dhcr7em1(IMPC)Mbp
Genetic
Background		 C57BL/6N-Dhcr7em1(IMPC)Mbp/MbpMmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dhcr7em1(IMPC)Mbp mutation (1 available); any Dhcr7 mutation (34 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system

embryo

growth/size/body
embryonic growth retardation ( J:211773 )
IMPC - UCD

homeostasis/metabolism
edema ( J:211773 )
IMPC - UCD

mortality/aging

vision/eye
microphthalmia ( J:211773 )
IMPC - UCD




Genotype
MGI:6461205
ht2
Allelic
Composition		 Dhcr7em1(IMPC)Mbp/Dhcr7+
Genetic
Background		 C57BL/6N-Dhcr7em1(IMPC)Mbp/MbpMmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dhcr7em1(IMPC)Mbp mutation (1 available); any Dhcr7 mutation (34 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
enlarged heart ( J:211773 )
IMPC - UCD

embryo

growth/size/body
enlarged heart ( J:211773 )
IMPC - UCD
enlarged spleen ( J:211773 )
IMPC - UCD

hematopoietic system
enlarged spleen ( J:211773 )
IMPC - UCD

immune system
enlarged spleen ( J:211773 )
IMPC - UCD

renal/urinary system
small kidney ( J:211773 )
IMPC - UCD

vision/eye
microphthalmia ( J:211773 )
IMPC - UCD




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory