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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Lig4m2Btlr
mutation 2, Bruce Beutler
MGI:6269402
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Lig4m2Btlr/Lig4m2Btlr C57BL/6J-Lig4m2Btlr MGI:6269404


Genotype
MGI:6269404
hm1
Allelic
Composition		 Lig4m2Btlr/Lig4m2Btlr
Genetic
Background		 C57BL/6J-Lig4m2Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lig4m2Btlr mutation (0 available); any Lig4 mutation (46 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased CD4-positive, alpha-beta T cell number ( J:267692 )
• reduced frequencies of naive CD4 T cells in CD4 T cells in the peripheral blood

hematopoietic system
decreased CD4-positive, alpha-beta T cell number ( J:267692 )
• reduced frequencies of naive CD4 T cells in CD4 T cells in the peripheral blood




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory