All Phenotypes Ptprc<m7Btlr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ptprc^m7Btlr
mutation 7, Bruce Beutler
MGI:6268383

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ptprc^m7Btlr/Ptprc^m7Btlr	C57BL/6J-Ptprc^m7Btlr	MGI:6268385

Allelic Composition	Ptprc^m7Btlr/Ptprc^m7Btlr
Genetic Background	C57BL/6J-Ptprc^m7Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptprc^m7Btlr mutation (0 available); any Ptprc mutation (188 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

increased B-1 B cell number ( J:267486 )

• in the peripheral blood

decreased B cell number ( J:267486 )

• in the peripheral blood

increased central memory CD4-positive, alpha-beta T cell number ( J:267486 )

• in the peripheral blood

increased effector memory CD4-positive, alpha-beta T cell number ( J:267486 )

• in the peripheral blood

increased central memory CD8 positive, alpha-beta T cell number ( J:267486 )

• in the peripheral blood

increased effector memory CD8-positive, alpha-beta T cell number ( J:267486 )

• in the peripheral blood

decreased CD8-positive, naive alpha-beta T cell number ( J:267486 )

• in the peripheral blood

decreased NK T cell number ( J:267486 )

• in the peripheral blood

decreased alpha-beta T cell number ( J:267486 )

• in the peripheral blood

decreased CD4-positive, alpha-beta T cell number ( J:267486 )

• in the peripheral blood

decreased CD8-positive, alpha-beta T cell number ( J:267486 )

• in the peripheral blood

hematopoietic system

increased B-1 B cell number ( J:267486 )

• in the peripheral blood

decreased B cell number ( J:267486 )

• in the peripheral blood

increased central memory CD4-positive, alpha-beta T cell number ( J:267486 )

• in the peripheral blood

increased effector memory CD4-positive, alpha-beta T cell number ( J:267486 )

• in the peripheral blood

increased central memory CD8 positive, alpha-beta T cell number ( J:267486 )

• in the peripheral blood

increased effector memory CD8-positive, alpha-beta T cell number ( J:267486 )

• in the peripheral blood

decreased CD8-positive, naive alpha-beta T cell number ( J:267486 )

• in the peripheral blood

decreased NK T cell number ( J:267486 )

• in the peripheral blood

decreased alpha-beta T cell number ( J:267486 )

• in the peripheral blood

decreased CD4-positive, alpha-beta T cell number ( J:267486 )

• in the peripheral blood

decreased CD8-positive, alpha-beta T cell number ( J:267486 )

• in the peripheral blood

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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