Phenotypes associated with this allele
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itm2cem1Nutt mutation
(0 available);
any
Itm2c mutation
(19 available)
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normal phenotype
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• mice are viable and fertile, show no overt physical defects or disease phenotype, and exhibit no differences in the development, maturation and differentiation of B-lymphocytes into antibody secreting cells or in immunoglobulin class-switch recombination relative to wild-type controls
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itm2cem1Nutt mutation
(0 available);
any
Itm2c mutation
(19 available)
Prdm1tm1Nutt mutation
(1 available);
any
Prdm1 mutation
(64 available)
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immune system
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N |
• mice show no significant differences in the frequency of bone marrow plasma cells, splenic plasma cells and splenic plasmablasts, or in the serum concentrations of IgM, IgG1, IgG2b, IgG2c, IgG3 or IgA relative to wild-type controls
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Analysis Tools