Phenotypes associated with this allele

• Allele Symbol: Tmem70^em2(IMPC)Bay
• Allele Name: endonuclease-mediated mutation 2, Baylor College of Medicine
• Allele ID: MGI:6257555
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tmem70^em2(IMPC)Bay/Tmem70^em2(IMPC)Bay	C57BL/6N-Tmem70^em2(IMPC)Bay/Bay	MGI:6288784
ht2	Tmem70^em2(IMPC)Bay/Tmem70^+	C57BL/6N-Tmem70^em2(IMPC)Bay/Bay	MGI:6288783

Genotype
MGI:6288784

hm1

• Allelic Composition: Tmem70^em2(IMPC)Bay/Tmem70^em2(IMPC)Bay
• Genetic Background: C57BL/6N-Tmem70^em2(IMPC)Bay/Bay

Data Sources

IMPC Data for Tmem70

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal pharyngeal arch morphology ( J:211773 )

IMPC - BCM

embryo

abnormal pharyngeal arch morphology ( J:211773 )

IMPC - BCM

abnormal embryo development ( J:211773 )

IMPC - BCM

abnormal embryo turning ( J:211773 )

IMPC - BCM

embryonic growth retardation ( J:211773 )

IMPC - BCM

abnormal embryo size ( J:211773 )

IMPC - BCM

abnormal neural tube morphology ( J:211773 )

IMPC - BCM

abnormal somite shape ( J:211773 )

IMPC - BCM

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - BCM

abnormal embryo size ( J:211773 )

IMPC - BCM

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - BCM

preweaning lethality, complete penetrance ( J:211773 )

IMPC - BCM

nervous system

abnormal neural tube morphology ( J:211773 )

IMPC - BCM

Genotype
MGI:6288783

ht2

• Allelic Composition: Tmem70^em2(IMPC)Bay/Tmem70⁺
• Genetic Background: C57BL/6N-Tmem70^em2(IMPC)Bay/Bay

Data Sources

IMPC Data for Tmem70

behavior/neurological

increased grip strength ( J:211773 )

IMPC - BCM

embryo

abnormal embryo turning ( J:211773 )

IMPC - BCM

embryonic growth retardation ( J:211773 )

IMPC - BCM

abnormal embryo size ( J:211773 )

IMPC - BCM

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - BCM

abnormal embryo size ( J:211773 )

IMPC - BCM