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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
+
wild type
MGI:6220870
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
Del(6Dlx6-Dlx5)1Tlu/+ Not Specified MGI:6209772
cx2
Del(6Dlx6-Dlx5)1Tlu/+
Mef2ctm1Eno/Mef2c+
involves: 129S7/SvEvBrd MGI:6209777


Genotype
MGI:6209772
ht1
Allelic
Composition
Del(6Dlx6-Dlx5)1Tlu/+
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
N
• heterozygotes appear normal at birth and generally survive to weaning; only 2 of 13 mice born are scored as dead or clearly cyanotic and dying, indicating that neonatal viability is not significantly affected relative to wild-type controls




Genotype
MGI:6209777
cx2
Allelic
Composition
Del(6Dlx6-Dlx5)1Tlu/+
Mef2ctm1Eno/Mef2c+
Genetic
Background
involves: 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(6Dlx6-Dlx5)1Tlu mutation (0 available); any Del(6Dlx6-Dlx5)1Tlu mutation (0 available)
Mef2ctm1Eno mutation (0 available); any Mef2c mutation (36 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• all (9 of 9) double heterozygous mice are clearly cyanotic at birth and die on postnatal day 0 (P0)

craniofacial
• at P0, mice exhibit a small, misshapen, and incomplete palate
• at P0, mice show an improper position of the tongue at the rear of the oral cavity

homeostasis/metabolism
• all mice are clearly cyanotic at birth

growth/size/body
• at P0, mice exhibit a small, misshapen, and incomplete palate
• at P0, mice show an improper position of the tongue at the rear of the oral cavity

digestive/alimentary system
• at P0, mice exhibit a small, misshapen, and incomplete palate
• at P0, mice show an improper position of the tongue at the rear of the oral cavity





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last database update
01/28/2026
MGI 6.24
The Jackson Laboratory