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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Wnk4tm3.1Suc
targeted mutation 3.1, Shinchi Uchida
MGI:6214838
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Wnk4tm3.1Suc/Wnk4tm3.1Suc involves: 129S4/SvJae * C57BL/6J MGI:6214840


Genotype
MGI:6214840
hm1
Allelic
Composition
Wnk4tm3.1Suc/Wnk4tm3.1Suc
Genetic
Background
involves: 129S4/SvJae * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Wnk4tm3.1Suc mutation (0 available); any Wnk4 mutation (56 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• mice on a low-salt diet exhibit lower systolic blood pressure than controls
• however, blood pressure is normal when mice are fed a normal or high-sodium diet

homeostasis/metabolism
• mice exhibit higher plasma pH
• mice exhibit lower plasma sodium levels
• however, plasma potassium levels are normal
• mice exhibit lower plasma chloride levels





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory