Phenotypes associated with this allele

• Allele Symbol: Atm^m1Btlr
• Allele Name: mutation 1, Bruce Beutler
• Allele ID: MGI:6200331
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Atm^m1Btlr/Atm^m1Btlr	C57BL/6J-Atm^m1Btlr	MGI:6200333

Genotype
MGI:6200333

hm1

• Allelic Composition: Atm^m1Btlr/Atm^m1Btlr
• Genetic Background: C57BL/6J-Atm^m1Btlr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

decreased T cell number ( J:265252 )

decreased CD4-positive, alpha-beta T cell number ( J:265252 )

decreased CD8-positive, alpha-beta T cell number ( J:265252 )

decreased single-positive T cell number ( J:265252 )

increased IgM level ( J:265252 )

• T-dependent antibody response to ovalbumin administered with aluminum hydroxide was also diminished

immune system

decreased T cell number ( J:265252 )

decreased CD4-positive, alpha-beta T cell number ( J:265252 )

decreased CD8-positive, alpha-beta T cell number ( J:265252 )

decreased single-positive T cell number ( J:265252 )

increased IgM level ( J:265252 )

• T-dependent antibody response to ovalbumin administered with aluminum hydroxide was also diminished

impaired humoral immune response ( J:265252 )

• T-dependent antibody response to ovalbumin administered with aluminum hydroxide was also diminished

decreased response to antigen ( J:265252 )

• T-dependent antibody response to ovalbumin administered with aluminum hydroxide was also diminished