All Phenotypes Elmo1<M1Btlr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Elmo1^M1Btlr
mutation 1, Bruce Beutler
MGI:6200276

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Elmo1^M1Btlr/Elmo1^M1Btlr	C57BL/6J-Elmo1^M1Btlr	MGI:6200278

Allelic Composition	Elmo1^M1Btlr/Elmo1^M1Btlr
Genetic Background	C57BL/6J-Elmo1^M1Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Elmo1^M1Btlr mutation (0 available); any Elmo1 mutation (60 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

increased B-1 B cell number ( J:265231 )

decreased B cell number ( J:265231 )

decreased IgM level ( J:265231 )

• diminished T-induced B cell response to TNP-Ficoll

immune system

increased B-1 B cell number ( J:265231 )

decreased B cell number ( J:265231 )

decreased IgM level ( J:265231 )

• diminished T-induced B cell response to TNP-Ficoll

impaired humoral immune response ( J:265231 )

• diminished T-induced B cell response to TNP-Ficoll

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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