Analysis Tools
homeostasis/metabolism
| N |
• glucose tolerance is normal
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Allele Symbol Allele Name Allele ID |
Ggcxtm1.1Kry targeted mutation 1.1, Gerard Karsenty MGI:6198558 |
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| Summary |
4 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• glucose tolerance is normal
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• glucose tolerance is normal
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• mice do not exhibit hypergonadism with normal sperm count, testis weight, epididymis weight, and seminal vesicle weight
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• when fed a high-fat diet
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• in fasted mice fed a high-fat diet
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• increased levels of GLU-OCN 3 to 4 times
• however, total and GLA-OCN levels are normal
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• in female and male mice when fed a high-fat diet or a normal diet
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• in female and male mice when fed a high-fat diet or a normal diet
• however, hyperinsulinemia when fed a high-fat diet is normal
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• when fed a high-fat diet
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• mice do not exhibit hypergonadism with normal sperm count, testis weight, epididymis weight, and seminal vesicle weight
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• GLA-OCN and total OCN levels decreased 75 and 10 times, respectively
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| N |
• mice exhibit normal trabecular and cortical bone density, numbers of osteoblast and osteoblasts, bone formation rates and osteoclastic activity
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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