All Phenotypes Prkdc<m12Btlr> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Prkdc^m12Btlr
mutation 12, Bruce Beutler
MGI:6198357

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Prkdc^m12Btlr/Prkdc^m12Btlr	C57BL/6J-Prkdc^m12Btlr	MGI:6198360

Allelic Composition	Prkdc^m12Btlr/Prkdc^m12Btlr
Genetic Background	C57BL/6J-Prkdc^m12Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prkdc^m12Btlr mutation (0 available); any Prkdc mutation (408 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased B cell number ( J:264708 )

decreased B-1 B cell number ( J:264708 )

increased NK cell number ( J:264708 )

increased central memory CD4-positive, alpha-beta T cell number ( J:264708 )

increased effector memory CD4-positive, alpha-beta T cell number ( J:264708 )

increased central memory CD8 positive, alpha-beta T cell number ( J:264708 )

decreased CD8-positive, naive alpha-beta T cell number ( J:264708 )

decreased T cell number ( J:264708 )

decreased CD4-positive, alpha-beta T cell number ( J:264708 )

decreased CD8-positive, alpha-beta T cell number ( J:264708 )

decreased NK T cell number ( J:264708 )

decreased single-positive T cell number ( J:264708 )

hematopoietic system

decreased B cell number ( J:264708 )

decreased B-1 B cell number ( J:264708 )

increased NK cell number ( J:264708 )

increased central memory CD4-positive, alpha-beta T cell number ( J:264708 )

increased effector memory CD4-positive, alpha-beta T cell number ( J:264708 )

increased central memory CD8 positive, alpha-beta T cell number ( J:264708 )

decreased CD8-positive, naive alpha-beta T cell number ( J:264708 )

decreased T cell number ( J:264708 )

decreased CD4-positive, alpha-beta T cell number ( J:264708 )

decreased CD8-positive, alpha-beta T cell number ( J:264708 )

decreased NK T cell number ( J:264708 )

decreased single-positive T cell number ( J:264708 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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