All Phenotypes Klhl14<tm1.1Jyw> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Klhl14^tm1.1Jyw
targeted mutation 1.1, Ji-Yang Wang
MGI:6191749

Summary

2 genotypes

Allelic Composition	Klhl14^tm1.1Jyw/Klhl14^tm1.1Jyw
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Klhl14^tm1.1Jyw mutation (0 available); any Klhl14 mutation (31 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• no mice are produced

Allelic Composition	Klhl14^tm1.1Jyw/Klhl14⁺
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Klhl14^tm1.1Jyw mutation (0 available); any Klhl14 mutation (31 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

immune system phenotype ( J:263511 )

N	• mice exhibit normal development, maturation and activation of spleen B-2 cells and basal serum immunoglobulin levels

decreased B-1a cell number ( J:263511 )

• in the peritoneal cavity

• however, B-1a cell survival and proliferation are normal

increased B-1b cell number ( J:263511 )

• in the peritoneal cavity

• however, B-1b cell survival and proliferation are normal

hematopoietic system

decreased B-1a cell number ( J:263511 )

• in the peritoneal cavity

• however, B-1a cell survival and proliferation are normal

increased B-1b cell number ( J:263511 )

• in the peritoneal cavity

• however, B-1b cell survival and proliferation are normal

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24