About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tssk4tm1.1Lgyu
targeted mutation 1.1, Long Yu
MGI:6191661
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tssk4tm1.1Lgyu/Tssk4tm1.1Lgyu B6.129(129S2)-Tssk4tm1.1Lgyu MGI:6191667


Genotype
MGI:6191667
hm1
Allelic
Composition		 Tssk4tm1.1Lgyu/Tssk4tm1.1Lgyu
Genetic
Background		 B6.129(129S2)-Tssk4tm1.1Lgyu
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tssk4tm1.1Lgyu mutation (0 available); any Tssk4 mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:263443 )
N
• female mice exhibit normal fertility
• male mice exhibit normal sexual behavior, testes and sperm count
abnormal sperm axoneme morphology ( J:263443 )
• one or more microtubule doublet is missing
abnormal sperm midpiece morphology ( J:263443 )
• bent in some sperm
• abnormally fused middle and principal pieces in some sperm
abnormal sperm principal piece morphology ( J:263443 )
• abnormally fused middle and principal pieces in some sperm
decreased litter size ( J:263443 )
• litter size is decreased 50% in male mice

cellular
abnormal sperm axoneme morphology ( J:263443 )
• one or more microtubule doublet is missing
abnormal sperm midpiece morphology ( J:263443 )
• bent in some sperm
• abnormally fused middle and principal pieces in some sperm
abnormal sperm principal piece morphology ( J:263443 )
• abnormally fused middle and principal pieces in some sperm




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory