Analysis Tools
reproductive system
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• males exhibit a sperm tail phenotype identical to that seen in Katnal2m1Anu homozygotes
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• elongating spermatids frequently exhibit abnormal nuclear morphology
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• males exhibit a manchette phenotype identical to that seen in Katnal2m1Anu homozygotes
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• multinucleated symplasts are frequently observed in the seminiferous epithelium
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• multinucleated symplasts are frequently observed in the seminiferous epithelium
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• total epididymal sperm content is reduced by 94.1% relative to control mice; however, testis weight and daily sperm output in the testes are normal, indicating a massive failure of spermiation
• retained elongated spermatids are often observed in stage IX tubules, unlike in control mice
• however, in contrast to Katnal2m1Anu homozygotes, tubulobulbar complex and residual body formation is similar to that observed in control mice
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cellular
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• males exhibit a sperm tail phenotype identical to that seen in Katnal2m1Anu homozygotes
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• elongating spermatids frequently exhibit abnormal nuclear morphology
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• males exhibit a manchette phenotype identical to that seen in Katnal2m1Anu homozygotes
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• multinucleated symplasts are frequently observed in the seminiferous epithelium
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endocrine/exocrine glands
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• multinucleated symplasts are frequently observed in the seminiferous epithelium
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