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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
H2az1tm1.1Hko
targeted mutation 1.1, Haruhiko Koseki
MGI:6163639
Summary 1 genotype


Genotype
MGI:6360248
cn1
Allelic
Composition
H2az1tm1.1Hko/H2az1tm1.1Hko
H2az2tm1.1Hko/H2az2tm1.1Hko
Tg(Vil1-cre)20Syr/0
Genetic
Background
B6.Cg-H2az1tm1.1Hko H2az2tm1.1Hko Tg(Vil1-cre)20Syr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2az1tm1.1Hko mutation (0 available); any H2az1 mutation (13 available)
H2az2tm1.1Hko mutation (0 available); any H2az2 mutation (26 available)
Tg(Vil1-cre)20Syr mutation (3 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body

digestive/alimentary system
• crypt cells fail to form intestinal organoids in vitro

endocrine/exocrine glands
• crypt cells fail to form intestinal organoids in vitro





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory