Phenotypes associated with this allele

• Allele Symbol: Dnmt3b^em1(IMPC)Mbp
• Allele Name: endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• Allele ID: MGI:6158518
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dnmt3b^em1(IMPC)Mbp/Dnmt3b^em1(IMPC)Mbp	C57BL/6N-Dnmt3b^em1(IMPC)Mbp/Ucd	MGI:6288429
ht2	Dnmt3b^em1(IMPC)Mbp/Dnmt3b^+	C57BL/6N-Dnmt3b^em1(IMPC)Mbp/Ucd	MGI:6262306

Genotype
MGI:6288429

hm1

• Allelic Composition: Dnmt3b^em1(IMPC)Mbp/Dnmt3b^em1(IMPC)Mbp
• Genetic Background: C57BL/6N-Dnmt3b^em1(IMPC)Mbp/Ucd

Data Sources

IMPC Data for Dnmt3b

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal placenta vasculature ( J:211773 )

IMPC - UCD

hemorrhage ( J:211773 )

♀

IMPC - UCD

craniofacial

abnormal craniofacial morphology ( J:211773 )

IMPC - UCD

abnormal facial morphology ( J:211773 )

♀

IMPC - UCD

cleft palate ( J:211773 )

IMPC - UCD

digestive/alimentary system

cleft palate ( J:211773 )

IMPC - UCD

embryo

embryonic growth retardation ( J:211773 )

IMPC - UCD

abnormal placenta morphology ( J:211773 )

IMPC - UCD

abnormal placenta vasculature ( J:211773 )

IMPC - UCD

growth/size/body

abnormal facial morphology ( J:211773 )

♀

IMPC - UCD

cleft palate ( J:211773 )

IMPC - UCD

embryonic growth retardation ( J:211773 )

IMPC - UCD

homeostasis/metabolism

edema ( J:211773 )

IMPC - UCD

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - UCD

vision/eye

microphthalmia ( J:211773 )

♀

IMPC - UCD

Genotype
MGI:6262306

ht2

• Allelic Composition: Dnmt3b^em1(IMPC)Mbp/Dnmt3b⁺
• Genetic Background: C57BL/6N-Dnmt3b^em1(IMPC)Mbp/Ucd

Data Sources

IMPC Data for Dnmt3b

cardiovascular system

hemorrhage ( J:211773 )

IMPC - UCD