Phenotypes associated with this allele

• Allele Symbol: Phf8^{em2(IMPC)Wtsi}
• Allele Name: endonuclease-mediated mutation 2, Wellcome Trust Sanger Institute
• Allele ID: MGI:6153728
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Phf8^em2(IMPC)Wtsi/Phf8^em2(IMPC)Wtsi	C57BL/6N-Phf8^em2(IMPC)Wtsi/Wtsi	MGI:6696853
ot2	Phf8^em2(IMPC)Wtsi/Y	C57BL/6N-Phf8^em2(IMPC)Wtsi/Wtsi	MGI:6263154

Genotype
MGI:6696853

hm1

• Allelic Composition: Phf8^{em2(IMPC)Wtsi}/Phf8^{em2(IMPC)Wtsi}
• Genetic Background: C57BL/6N-Phf8^{em2(IMPC)Wtsi}/Wtsi

Data Sources

IMPC Data for Phf8

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

increased mean corpuscular hemoglobin ( J:211773 )

♀

IMPC - WTSI

homeostasis/metabolism

increased circulating cholesterol level ( J:211773 )

♀

IMPC - WTSI

increased circulating HDL cholesterol level ( J:211773 )

♀

IMPC - WTSI

increased circulating LDL cholesterol level ( J:211773 )

♀

IMPC - WTSI

Genotype
MGI:6263154

ot2

• Allelic Composition: Phf8^{em2(IMPC)Wtsi}/Y
• Genetic Background: C57BL/6N-Phf8^{em2(IMPC)Wtsi}/Wtsi

Data Sources

IMPC Data for Phf8

hematopoietic system

decreased erythrocyte cell number ( J:211773 )

♂

IMPC - WTSI

increased mean corpuscular hemoglobin ( J:211773 )

♂

IMPC - WTSI