Phenotypes associated with this allele

• Allele Symbol: Nsmce1^{em1(IMPC)Wtsi}
• Allele Name: endonuclease-mediated mutation 1, Wellcome Trust Sanger Institute
• Allele ID: MGI:6153567
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Nsmce1^em1(IMPC)Wtsi/Nsmce1^em1(IMPC)Wtsi	C57BL/6N-Nsmce1^em1(IMPC)Wtsi/Wtsi	MGI:6480534
ht2	Nsmce1^em1(IMPC)Wtsi/Nsmce1^+	C57BL/6N-Nsmce1^em1(IMPC)Wtsi/Wtsi	MGI:6408541

Genotype
MGI:6480534

hm1

• Allelic Composition: Nsmce1^{em1(IMPC)Wtsi}/Nsmce1^{em1(IMPC)Wtsi}
• Genetic Background: C57BL/6N-Nsmce1^{em1(IMPC)Wtsi}/Wtsi

Data Sources

IMPC Data for Nsmce1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

embryonic growth retardation ( J:211773 )

IMPC - CCP-IMG

abnormal embryo size ( J:211773 )

IMPC - CCP-IMG

growth/size/body

embryonic growth retardation ( J:211773 )

IMPC - CCP-IMG

abnormal embryo size ( J:211773 )

IMPC - CCP-IMG

mortality/aging

embryonic lethality prior to tooth bud stage ( J:211773 )

IMPC - CCP-IMG

preweaning lethality, complete penetrance ( J:211773 )

IMPC - CCP-IMG

Genotype
MGI:6408541

ht2

• Allelic Composition: Nsmce1^{em1(IMPC)Wtsi}/Nsmce1⁺
• Genetic Background: C57BL/6N-Nsmce1^{em1(IMPC)Wtsi}/Wtsi

Data Sources

IMPC Data for Nsmce1

growth/size/body

enlarged spleen ( J:211773 )

♀

IMPC - CCP-IMG

hematopoietic system

abnormal spleen morphology ( J:211773 )

♀

IMPC - CCP-IMG

enlarged spleen ( J:211773 )

♀

IMPC - CCP-IMG

homeostasis/metabolism

increased circulating triglyceride level ( J:211773 )

♂

IMPC - CCP-IMG

increased circulating total protein level ( J:211773 )

IMPC - CCP-IMG

immune system

abnormal spleen morphology ( J:211773 )

♀

IMPC - CCP-IMG

enlarged spleen ( J:211773 )

♀

IMPC - CCP-IMG

reproductive system

abnormal uterus morphology ( J:211773 )

♀

IMPC - CCP-IMG

hydrometra ( J:211773 )

♀

IMPC - CCP-IMG